Novel CD8 T Cell Alloreactivities in CCR5-Deficient Recipients of Class II MHC Disparate Kidney Grafts

Recipient CD4 T regulatory cells inhibit the acute T cell-mediated rejection of renal allografts in wild type mice. The survival of single class II MHC-disparate H-2(bm12) renal allografts was tested in B6.CCR5(−/−) recipients, which have defects in Treg activities constraining alloimmune responses....

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Bibliografiska uppgifter
Huvudupphovsmän: Ishii, Daisuke, Rosenblum, Joshua M., Nozaki, Taiji, Schenk, Austin D., Setoguchi, Kiyoshi, Su, Charles A., Gorbacheva, Victoria, Baldwin, William M., Valujskikh, Anna, Fairchild, Robert L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170018/
https://ncbi.nlm.nih.gov/pubmed/25172484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303256
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