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Contribution of TCR signaling strength to CD8+ T cell peripheral tolerance mechanisms

Peripheral tolerance mechanisms are in place to prevent T cells from mediating aberrant immune responses directed against self and environmental antigens. Mechanisms involved in the induction of peripheral tolerance include T cell intrinsic pathways, such as anergy or deletion, or exogenous toleranc...

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Main Authors: Smith, Trevor R.F., Verdeil, Gregory, Marquardt, Kristi, Sherman, Linda A.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170000/
https://ncbi.nlm.nih.gov/pubmed/25156361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401194
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