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Complement activation by ligand-driven juxtaposition of discrete pattern recognition complexes
Defining mechanisms governing translation of molecular binding events into immune activation is central to understanding immune function. In the lectin pathway of complement, the pattern recognition molecules (PRMs) mannan-binding lectin (MBL) and ficolins complexed with the MBL-associated serine pr...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4169954/ https://ncbi.nlm.nih.gov/pubmed/25197071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406849111 |
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