Complement activation by ligand-driven juxtaposition of discrete pattern recognition complexes

Defining mechanisms governing translation of molecular binding events into immune activation is central to understanding immune function. In the lectin pathway of complement, the pattern recognition molecules (PRMs) mannan-binding lectin (MBL) and ficolins complexed with the MBL-associated serine pr...

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Detalhes bibliográficos
Main Authors: Degn, Søren E., Kjaer, Troels R., Kidmose, Rune T., Jensen, Lisbeth, Hansen, Annette G., Tekin, Mustafa, Jensenius, Jens C., Andersen, Gregers R., Thiel, Steffen
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169954/
https://ncbi.nlm.nih.gov/pubmed/25197071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406849111
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