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C-terminal domain small phosphatase 1 and MAP kinase reciprocally control REST stability and neuronal differentiation
The repressor element 1 (RE1) silencing transcription factor (REST) in stem cells represses hundreds of genes essential to neuronal function. During neurogenesis, REST is degraded in neural progenitors to promote subsequent elaboration of a mature neuronal phenotype. Prior studies indicate that part...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4169941/ https://ncbi.nlm.nih.gov/pubmed/25197063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414770111 |
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