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C-terminal domain small phosphatase 1 and MAP kinase reciprocally control REST stability and neuronal differentiation
The repressor element 1 (RE1) silencing transcription factor (REST) in stem cells represses hundreds of genes essential to neuronal function. During neurogenesis, REST is degraded in neural progenitors to promote subsequent elaboration of a mature neuronal phenotype. Prior studies indicate that part...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4169941/ https://ncbi.nlm.nih.gov/pubmed/25197063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414770111 |
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