SIN3 is critical for stress resistance and modulates adult lifespan

Coordinate control of gene activity is critical for fitness and longevity of an organism. The SIN3 histone deacetylase (HDAC) complex functions as a transcriptional repressor of many genes. SIN3-regulated genes include those that encode proteins affecting multiple aspects of mitochondrial function,...

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Hlavní autoři: Barnes, Valerie L., Bhat, Abhineeth, Unnikrishnan, Archana, Heydari, Ahmad R., Arking, Robert, Pile, Lori A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2014
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169859/
https://ncbi.nlm.nih.gov/pubmed/25133314
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