SIN3 is critical for stress resistance and modulates adult lifespan

Coordinate control of gene activity is critical for fitness and longevity of an organism. The SIN3 histone deacetylase (HDAC) complex functions as a transcriptional repressor of many genes. SIN3-regulated genes include those that encode proteins affecting multiple aspects of mitochondrial function,...

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Autori principali: Barnes, Valerie L., Bhat, Abhineeth, Unnikrishnan, Archana, Heydari, Ahmad R., Arking, Robert, Pile, Lori A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2014
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169859/
https://ncbi.nlm.nih.gov/pubmed/25133314
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