CAPN5 gene silencing by short hairpin RNA interference

BACKGROUND: The purpose of this project was to identify short hairpin RNA (shRNA) sequences that can suppress expression of human CAPN5 in which gain-of-function mutants cause autosomal dominant neovascular inflammatory vitreoretinopathy (ADNIV). We created HEK293T cells that stably express an ADNIV...

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Bibliografische gegevens
Hoofdauteurs: Nelson, Nnamdi G, Skeie, Jessica M, Muradov, Hakim, Rowell, Hannah A, Seo, Seongjin, Mahajan, Vinit B
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169796/
https://ncbi.nlm.nih.gov/pubmed/25216694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-7-642
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