Short hairpin RNA interference therapy for ischemic heart disease

BACKGROUND: During hypoxia, upregulation of hypoxia inducible factor-1 alpha (HIF-1α) transcriptional factor can activate several downstream angiogenic genes. However, HIF-1α is naturally degraded by prolyl hydroxylase-2 (PHD2) protein. Here we hypothesize that short hairpin RNA (shRNA) interference...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Huang, Mei, Chan, Denise, Jia, Fangjun, Xie, Xiaoyan, Li, Zongjin, Hoyt, Grant, Robbins, Robert C., Chen, Xiaoyuan, Giaccia, Amato, Wu, Joseph C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657507/
https://ncbi.nlm.nih.gov/pubmed/18824759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.107.760785
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados