TLR5-Mediated Sensing of Gut Microbiota Is Necessary for Antibody Responses to Seasonal Influenza Vaccination

Systems biological analysis of immunity to the trivalent inactivated influenza vaccine (TIV) in humans revealed a correlation between early expression of TLR5 and the magnitude of the antibody response. Vaccination of Trl5(−/−) mice resulted in reduced antibody titers and lower frequencies of plasma...

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Bibliografische gegevens
Hoofdauteurs: Oh, Jason Z., Ravindran, Rajesh, Chassaing, Benoit, Carvalho, Frederic A., Maddur, Mohan S., Bower, Maureen, Hakimpour, Paul, Gill, Kiran P., Nakaya, Helder I., Yarovinsky, Felix, Sartor, R. Balfour, Gewirtz, Andrew T., Pulendran, Bali
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169736/
https://ncbi.nlm.nih.gov/pubmed/25220212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.08.009
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