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Zinc pyrithione impairs zinc homeostasis and upregulates stress response gene expression in reconstructed human epidermis
Zinc ion homeostasis plays an important role in human cutaneous biology where it is involved in epidermal differentiation and barrier function, inflammatory and antimicrobial regulation, and wound healing. Zinc-based compounds designed for topical delivery therefore represent an important class of c...
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Format: | Artigo |
Jezik: | Inglês |
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2011
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4169675/ https://ncbi.nlm.nih.gov/pubmed/21424779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10534-011-9441-6 |
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