Subfertility and growth restriction in a new galactose-1 phosphate uridylyltransferase (GALT) - deficient mouse model

The first GalT gene knockout (KO) mouse model for Classic Galactosemia (OMIM 230400) accumulated some galactose and its metabolites upon galactose challenge, but was seemingly fertile and symptom free. Here we constructed a new GalT gene-trapped mouse model by injecting GalT gene-trapped mouse embry...

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Detalhes bibliográficos
Main Authors: Tang, Manshu, Siddiqi, Anwer, Witt, Benjamin, Yuzyuk, Tatiana, Johnson, Britt, Fraser, Nisa, Chen, Wyman, Rascon, Rafael, Yin, Xue, Goli, Harish, Bodamer, Olaf A, Lai, Kent
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169538/
https://ncbi.nlm.nih.gov/pubmed/24549051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2014.12
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