Genome-Wide Meta-Analysis of Myopia and Hyperopia Provides Evidence for Replication of 11 Loci

Refractive error (RE) is a complex, multifactorial disorder characterized by a mismatch between the optical power of the eye and its axial length that causes object images to be focused off the retina. The two major subtypes of RE are myopia (nearsightedness) and hyperopia (farsightedness), which re...

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Autori principali: Simpson, Claire L., Wojciechowski, Robert, Oexle, Konrad, Murgia, Federico, Portas, Laura, Li, Xiaohui, Verhoeven, Virginie J. M., Vitart, Veronique, Schache, Maria, Hosseini, S. Mohsen, Hysi, Pirro G., Raffel, Leslie J., Cotch, Mary Frances, Chew, Emily, Klein, Barbara E. K., Klein, Ronald, Wong, Tien Yin, van Duijn, Cornelia M., Mitchell, Paul, Saw, Seang Mei, Fossarello, Maurizio, Wang, Jie Jin, Polašek, Ozren, Campbell, Harry, Rudan, Igor, Oostra, Ben A., Uitterlinden, André G., Hofman, Albert, Rivadeneira, Fernando, Amin, Najaf, Karssen, Lennart C., Vingerling, Johannes R., Döring, Angela, Bettecken, Thomas, Bencic, Goran, Gieger, Christian, Wichmann, H.-Erich, Wilson, James F., Venturini, Cristina, Fleck, Brian, Cumberland, Phillippa M., Rahi, Jugnoo S., Hammond, Chris J., Hayward, Caroline, Wright, Alan F., Paterson, Andrew D., Baird, Paul N., Klaver, Caroline C. W., Rotter, Jerome I., Pirastu, Mario, Meitinger, Thomas, Bailey-Wilson, Joan E., Stambolian, Dwight
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169415/
https://ncbi.nlm.nih.gov/pubmed/25233373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107110
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