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Alveolar Hypoxia Promotes Murine Lung Tumor Growth Through A VEGFR-2/EGFR Dependent Mechanism

Patients with chronic obstructive pulmonary disease (COPD) are at increased risk for the development of lung cancer, the mechanisms for which are incompletely understood. We hypothesized that the hypoxic pulmonary microenvironment present in COPD would augment lung carcinogenesis. Mice were subjecte...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Karoor, Vijaya, Le, Mysan, Merrick, Daniel, Fagan, Karen A., Dempsey, Edward C., Miller, York E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169262/
https://ncbi.nlm.nih.gov/pubmed/22700853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-12-0069-T
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