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Out of Balance: R-loops in Human Disease
R-loops are cellular structures composed of an RNA/DNA hybrid, which is formed when the RNA hybridises to a complementary DNA strand and a displaced single-stranded DNA. R-loops have been detected in various organisms from bacteria to mammals and play crucial roles in regulating gene expression, DNA...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4169248/ https://ncbi.nlm.nih.gov/pubmed/25233079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004630 |
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