High Density SNP Screen in A Large Multiplex Neural Tube Defect Family Refines Linkage to Loci at 7p21-Pter And 2q33.1-35

BACKGROUND: Neural tube defects (NTDs) are considered complex with both genetic and environmental factors implicated. To date, no major causative genes have been identified in humans despite several investigations. The first genomewide screen in NTDs (Rampersaud et al. 2005) demonstrated evidence of...

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Main Authors: Stamm, Demetra S., Rampersaud, Evadnie, Slifer, Susan H., Mehltretter, Lorraine, Siegel, Deborah G., Xie, Jianzhen, Hu-Lince, Diane, Craig, David W., Stephan, Dietrich A., George, Timothy M., Gilbert, John R., Speer, Marcy C.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169147/
https://ncbi.nlm.nih.gov/pubmed/16933213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.20272
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