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Multiplex SNP Discrimination

Multiplex hybridization reactions of perfectly matched duplexes and duplexes containing a single basepair mismatch (SNPs) were investigated on DNA microarrays. Effects of duplex length, G-C percentage, and relative position of the SNP on duplex hybridization and SNP resolution were determined. Our t...

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Detalhes bibliográficos
Main Authors: Fish, Daniel J., Horne, M. Todd, Searles, Robert P., Brewood, Greg P., Benight, Albert S.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853129/
https://ncbi.nlm.nih.gov/pubmed/17369420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.105320
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