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DNA multiplex hybridization on microarrays and thermodynamic stability in solution: a direct comparison

Hybridization intensities of 30 distinct short duplex DNAs measured on spotted microarrays, were directly compared with thermodynamic stabilities measured in solution. DNA sequences were designed to promote formation of perfect match, or hybrid duplexes containing tandem mismatches. Thermodynamic pa...

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Detalhes bibliográficos
Main Authors: Fish, Daniel J., Horne, M. Todd, Brewood, Greg P., Goodarzi, Jim P., Alemayehu, Saba, Bhandiwad, Ashwini, Searles, Robert P., Benight, Albert S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175334/
https://ncbi.nlm.nih.gov/pubmed/17947320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm865
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