Differentiating the roles of STAT5B and STAT5A in human CD4(+) T cells

STAT5A and STAT5B are highly homologous proteins whose distinctive roles in human immunity remain unclear. However, STAT5A sufficiency cannot compensate for STAT5B defects, and human STAT5B deficiency, a rare autosomal recessive primary immunodeficiency, is characterized by chronic lung disease, gro...

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Hauptverfasser: Jenks, Jennifer A., Seki, Scott, Kanai, Takahiro, Huang, Jennifer, Morgan, Alexander A., Scalco, Renata C., Nath, Ruhi, Bucayu, Robert, Wit, Jan M., Al-Herz, Waleed, Ramadan, Dina, Jorge, Alexander A., Bacchetta, Rosa, Hwa, Vivian, Rosenfeld, Ron, Nadeau, Kari C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169138/
https://ncbi.nlm.nih.gov/pubmed/23773921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2013.04.014
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