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Calpain 1 Knockdown Improves Tissue Sparing and Functional Outcomes after Spinal Cord Injury in Rats

To evaluate the hypothesis that calpain 1 knockdown would reduce pathological damage and functional deficits after spinal cord injury (SCI), we developed lentiviral vectors encoding calpain 1 shRNA and eGFP as a reporter (LV-CAPN1 shRNA). The ability of LV-CAPN1 shRNA to knockdown calpain 1 was conf...

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Main Authors: Yu, Chen Guang, Li, Yanzhang, Raza, Kashif, Yu, Xin Xin, Ghoshal, Sarbani, Geddes, James W.
格式: Artigo
語言:Inglês
出版: Mary Ann Liebert, Inc. 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169127/
https://ncbi.nlm.nih.gov/pubmed/23102374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2012.2561
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