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Azithromycin drives alternative macrophage activation and improves recovery and tissue sparing in contusion spinal cord injury

BACKGROUND: Macrophages persist indefinitely at sites of spinal cord injury (SCI) and contribute to both pathological and reparative processes. While the alternative, anti-inflammatory (M2) phenotype is believed to promote cell protection, regeneration, and plasticity, pro-inflammatory (M1) macropha...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Zhang, Bei, Bailey, William M., Kopper, Timothy J., Orr, Michael B., Feola, David J., Gensel, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657208/
https://ncbi.nlm.nih.gov/pubmed/26597676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0440-3
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