Monovalent IgG4 molecules: Immunoglobulin Fc mutations that result in a monomeric structure

Antibodies have become the fastest growing class of biological therapeutics, in part due to their exquisite specificity and ability to modulate protein-protein interactions with a high biological potency. The relatively large size and bivalency of antibodies, however, limits their use as therapeutic...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Wilkinson, Ian C., Fowler, Susan B., Machiesky, LeeAnn, Miller, Kenneth, Hayes, David B., Adib, Morshed, Her, Cheng, Borrok, M. Jack, Tsui, Ping, Burrell, Matthew, Corkill, Dominic J., Witt, Susanne, Lowe, David C., Webster, Carl I.
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2013
Assuntos:
Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169034/
https://ncbi.nlm.nih.gov/pubmed/23567207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.23941
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares