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Monovalent IgG4 molecules: Immunoglobulin Fc mutations that result in a monomeric structure
Antibodies have become the fastest growing class of biological therapeutics, in part due to their exquisite specificity and ability to modulate protein-protein interactions with a high biological potency. The relatively large size and bivalency of antibodies, however, limits their use as therapeutic...
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| Autori principali: | , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4169034/ https://ncbi.nlm.nih.gov/pubmed/23567207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.23941 |
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