Monovalent IgG4 molecules: Immunoglobulin Fc mutations that result in a monomeric structure

Antibodies have become the fastest growing class of biological therapeutics, in part due to their exquisite specificity and ability to modulate protein-protein interactions with a high biological potency. The relatively large size and bivalency of antibodies, however, limits their use as therapeutic...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wilkinson, Ian C., Fowler, Susan B., Machiesky, LeeAnn, Miller, Kenneth, Hayes, David B., Adib, Morshed, Her, Cheng, Borrok, M. Jack, Tsui, Ping, Burrell, Matthew, Corkill, Dominic J., Witt, Susanne, Lowe, David C., Webster, Carl I.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169034/
https://ncbi.nlm.nih.gov/pubmed/23567207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.23941
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados