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DPPA3 prevents cytosine hydroxymethylation of the maternal pronucleus and is required for normal development in bovine embryos
Dppa3 has been described in mice as an important maternal factor contributed by the oocyte that participates in protecting the maternal genome from oxidation of methylated cytosines (5mC) to hydroxymethylated cytosines (5hmC). Dppa3 is also required for normal mouse preimplantation development. This...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4169019/ https://ncbi.nlm.nih.gov/pubmed/25147917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.32087 |
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