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DPPA3 prevents cytosine hydroxymethylation of the maternal pronucleus and is required for normal development in bovine embryos

Dppa3 has been described in mice as an important maternal factor contributed by the oocyte that participates in protecting the maternal genome from oxidation of methylated cytosines (5mC) to hydroxymethylated cytosines (5hmC). Dppa3 is also required for normal mouse preimplantation development. This...

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Autori principali: Bakhtari, Azizollah, Ross, Pablo J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169019/
https://ncbi.nlm.nih.gov/pubmed/25147917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.32087
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