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Spatial Heterogeneity and Peptide Availability Determine CTL Killing Efficiency In Vivo
The rate at which a cytotoxic T lymphocyte (CTL) can survey for infected cells is a key ingredient of models of vertebrate immune responses to intracellular pathogens. Estimates have been obtained using in vivo cytotoxicity assays in which peptide-pulsed splenocytes are killed by CTL in the spleens...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4168979/ https://ncbi.nlm.nih.gov/pubmed/25233372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003805 |
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