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Examining Variable Domain Orientations in Antigen Receptors Gives Insight into TCR-Like Antibody Design

The variable domains of antibodies and T-Cell receptors (TCRs) share similar structures. Both molecules act as sensors for the immune system but recognise their respective antigens in different ways. Antibodies bind to a diverse set of antigenic shapes whilst TCRs only recognise linear peptides pres...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Dunbar, James, Knapp, Bernhard, Fuchs, Angelika, Shi, Jiye, Deane, Charlotte M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168974/
https://ncbi.nlm.nih.gov/pubmed/25233457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003852
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