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Pax5 (BSAP) regulates the murine immunoglobulin 3' alpha enhancer by suppressing binding of NF-alpha P, a protein that controls heavy chain transcription.

The Pax5 transcription factor BSAP (B-cell-specific activator protein) is known to bind to and repress the activity of the immunoglobulin heavy chain 3' alpha enhancer. We have detected an element--designated alpha P--that lies approximately 50 bp downstream of the BSAP binding site 1 and is require...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Neurath, M F, Max, E E, Strober, W
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41689/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7777508/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.12.5336
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