CCR7 Is Critical for the Induction and Maintenance of Th17 Immunity in Dry Eye Disease

PURPOSE. We characterized antigen-presenting cell (APC)–relevant chemokine receptor expression in dry eye disease (DED), and investigated the effect of topical CC chemokine receptor (CCR)-7 blockade specifically on Th17 cell immunity and dry eye disease severity. METHODS. We induced DED in female C5...

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Main Authors: Kodati, Shilpa, Chauhan, Sunil K., Chen, Yihe, Dohlman, Thomas H., Karimian, Parisa, Saban, Daniel, Dana, Reza
Format: Artigo
Language:Inglês
Published: The Association for Research in Vision and Ophthalmology 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168741/
https://ncbi.nlm.nih.gov/pubmed/25139737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-14481
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