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The CCR6/CCL20 Axis Mediates Th17 Cell Migration to the Ocular Surface in Dry Eye Disease

PURPOSE. Th17 cells are believed to be the primary effector cells in the pathogenesis of dry eye disease (DED). However, the mechanisms by which Th17 cells migrate from the lymphoid tissues to the ocular surface are unknown. The purpose of this study was to investigate the role of the C–C chemokine...

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Bibliografske podrobnosti
Main Authors: Dohlman, Thomas H., Chauhan, Sunil K., Kodati, Shilpa, Hua, Jing, Chen, Yihe, Omoto, Masahiro, Sadrai, Zahra, Dana, Reza
Format: Artigo
Jezik:Inglês
Izdano: The Association for Research in Vision and Ophthalmology 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681477/
https://ncbi.nlm.nih.gov/pubmed/23702781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-11216
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