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Near-optimal assembly for shotgun sequencing with noisy reads

Recent work identified the fundamental limits on the information requirements in terms of read length and coverage depth required for successful de novo genome reconstruction from shotgun sequencing data, based on the idealistic assumption of no errors in the reads (noiseless reads). In this work, w...

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Autors principals: Lam, Ka-Kit, Khalak, Asif, Tse, David
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168708/
https://ncbi.nlm.nih.gov/pubmed/25252708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-S9-S4
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