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Assembly-free genome comparison based on next-generation sequencing reads and variable length patterns

BACKGROUND: With the advent of Next-Generation Sequencing technologies (NGS), a large amount of short read data has been generated. If a reference genome is not available, the assembly of a template sequence is usually challenging because of repeats and the short length of reads. When NGS reads cann...

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Autors principals: Comin, Matteo, Schimd, Michele
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168702/
https://ncbi.nlm.nih.gov/pubmed/25252700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-S9-S1
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