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Methodology for the analysis of rare genetic variation in genome-wide association and re-sequencing studies of complex human traits

Genome-wide association studies have been successful in identifying common variants that impact complex human traits and diseases. However, despite this success, the joint effects of these variants explain only a small proportion of the genetic variance in these phenotypes, leading to speculation th...

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Autors principals: Moutsianas, Loukas, Morris, Andrew P.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168660/
https://ncbi.nlm.nih.gov/pubmed/24916163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bfgp/elu012
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