Absence of STAT1 in donor-derived plasmacytoid dendritic cells results in increased STAT3 and attenuates murine GVHD

Selective targeting of non-T cells, including antigen-presenting cells (APCs), is a potential strategy to prevent graft-versus-host-disease (GVHD) but to maintain graft-versus-tumor (GVT) effects. Because type I and II interferons signal through signal transducer and activator of transcription-1 (ST...

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Bibliographic Details
Main Authors: Capitini, Christian M., Nasholm, Nicole M., Chien, Christopher D., Larabee, Shannon M., Qin, Haiying, Song, Young K., Klover, Peter J., Hennighausen, Lothar, Khan, Javed, Fry, Terry J.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2014
Subjects:
Transplantation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168352/
https://ncbi.nlm.nih.gov/pubmed/25079358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-05-500876
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