Bone marrow deficient in IFN-γ signaling selectively reverses GVHD-associated immunosuppression and enhances a tumor-specific GVT effect

Vaccine-based expansion of T cells is one approach to enhance the graft-versus-tumor effect of allogeneic bone marrow transplantation (BMT), but the complex immunobiology of the allogeneic environment on responses to tumor vaccines has not been well characterized. We hypothesized that subclinical gr...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Capitini, Christian M., Herby, Sarah, Milliron, Matthew, Anver, Miriam R., Mackall, Crystal L., Fry, Terry J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2009
Ämnen:
Transplantation
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686147/
https://ncbi.nlm.nih.gov/pubmed/19258593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-11-187385
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk