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Bone marrow deficient in IFN-γ signaling selectively reverses GVHD-associated immunosuppression and enhances a tumor-specific GVT effect

Vaccine-based expansion of T cells is one approach to enhance the graft-versus-tumor effect of allogeneic bone marrow transplantation (BMT), but the complex immunobiology of the allogeneic environment on responses to tumor vaccines has not been well characterized. We hypothesized that subclinical gr...

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Detalhes bibliográficos
Main Authors: Capitini, Christian M., Herby, Sarah, Milliron, Matthew, Anver, Miriam R., Mackall, Crystal L., Fry, Terry J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686147/
https://ncbi.nlm.nih.gov/pubmed/19258593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-11-187385
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