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Functional characterization of the human dendritic cell immunodeficiency associated with the IRF8(K108E) mutation
We have previously reported on a unique patient in whom homozygosity for a mutation at IRF8 (IRF8(K108E)) causes a severe immunodeficiency. Laboratory evaluation revealed a highly unusual myeloid compartment, remarkable for the complete absence of CD14(+) and CD16(+) monocytes, absence of CD11c(+) c...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4168344/ https://ncbi.nlm.nih.gov/pubmed/25122610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-570879 |
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