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Hemoglobinopathic Erythrocytes Affect the Intraerythrocytic Multiplication of Plasmodium falciparum In Vitro

Background. The mechanisms by which α-thalassemia and sickle cell traits confer protection from severe Plasmodium falciparum malaria are not yet fully elucidated. We hypothesized that hemoglobinopathic erythrocytes reduce the intraerythrocytic multiplication of P. falciparum, potentially delaying th...

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Main Authors: Glushakova, Svetlana, Balaban, Amanda, McQueen, Philip G., Coutinho, Rosane, Miller, Jeffery L., Nossal, Ralph, Fairhurst, Rick M., Zimmerberg, Joshua
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168301/
https://ncbi.nlm.nih.gov/pubmed/24688070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu203
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