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Hemoglobinopathic Erythrocytes Affect the Intraerythrocytic Multiplication of Plasmodium falciparum In Vitro

Background. The mechanisms by which α-thalassemia and sickle cell traits confer protection from severe Plasmodium falciparum malaria are not yet fully elucidated. We hypothesized that hemoglobinopathic erythrocytes reduce the intraerythrocytic multiplication of P. falciparum, potentially delaying th...

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Detalhes bibliográficos
Main Authors: Glushakova, Svetlana, Balaban, Amanda, McQueen, Philip G., Coutinho, Rosane, Miller, Jeffery L., Nossal, Ralph, Fairhurst, Rick M., Zimmerberg, Joshua
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168301/
https://ncbi.nlm.nih.gov/pubmed/24688070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu203
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