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Sotalol permeability in cultured-cell, rat intestine and PAMPA system
PURPOSE: To clarify sotalol’s classification in the BCS versus BDDCS systems through cellular, rat everted sac and PAMPA permeability studies. METHODS: Studies were carried out in Madin Darby canine kidney (MDCK) and MDR1-transfected MDCK (MDCK-MDR1) cell lines, rat everted gut sacs and the Parallel...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4167886/ https://ncbi.nlm.nih.gov/pubmed/22350803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-012-0699-3 |
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