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Sotalol permeability in cultured-cell, rat intestine and PAMPA system

PURPOSE: To clarify sotalol’s classification in the BCS versus BDDCS systems through cellular, rat everted sac and PAMPA permeability studies. METHODS: Studies were carried out in Madin Darby canine kidney (MDCK) and MDR1-transfected MDCK (MDCK-MDR1) cell lines, rat everted gut sacs and the Parallel...

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書誌詳細
主要な著者: LIU, WEI, OKOCHI, HIDEAKI, BENET, LESLIE Z., ZHAI, SUO-DI
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167886/
https://ncbi.nlm.nih.gov/pubmed/22350803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-012-0699-3
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