Aldose Reductase Inhibition Suppresses the Expression of Th2 Cytokines and Airway Inflammation in Ovalbumin-Induced Asthma in Mice()

Airway inflammation induced by reactive oxygen species-mediated activation of redox-sensitive transcription factors is the hallmark of asthma, a prevalent chronic respiratory disease. In various cellular and animal models, we have recently demonstrated that, in response to multiple stimuli, aldose r...

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Main Authors: Yadav, Umesh C. S., Naura, Amarjit S., Aguilera-Aguirre, Leopoldo, Ramana, Kota V., Boldogh, Istvan, Sur, Sanjiv, Boulares, Hamid A., Srivastava, Satish K.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167870/
https://ncbi.nlm.nih.gov/pubmed/19752229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901177
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