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Aldose reductase deficiency in mice protects from ragweed pollen extract (RWE)-induced allergic asthma
BACKGROUND: Childhood hospitalization related to asthma remains at historically high levels, and its incidence is on the rise world-wide. Previously, we have demonstrated that aldose reductase (AR), a regulatory enzyme of polyol pathway, is a major mediator of allergen-induced asthma pathogenesis in...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3233521/ https://ncbi.nlm.nih.gov/pubmed/22054012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-145 |
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