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Selenoprotein K form an intermolecular diselenide bond with unusually high redox potential

Selenoprotein K (SelK) is a membrane protein involved in antioxidant defense, calcium regulation and the ER-associated protein degradation pathway. We found that SelK exhibits a peroxidase activity with a rate that is low but within the range of other peroxidases. Notably, SelK reduced hydrophobic s...

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Autores principales: Liu, Jun, Zhang, Zhengqi, Rozovsky, Sharon
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167758/
https://ncbi.nlm.nih.gov/pubmed/25117454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2014.07.037
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