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Recent progress with microtubule stabilizers: new compounds, binding modes and cellular activities

Nature has yielded numerous classes of chemically distinct microtubule stabilizers. Several of these, including paclitaxel (Taxol) and docetaxel (Taxotere), are important drugs used in the treatment of cancer. New microtubule stabilizers and novel formulations of these agents continue to provide adv...

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Detalhes bibliográficos
Main Authors: Rohena, Cristina C., Mooberry, Susan L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167679/
https://ncbi.nlm.nih.gov/pubmed/24481420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3np70092e
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