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Increased Notch signaling inhibits anoikis and stimulates proliferation of prostate luminal epithelial cells

The prostate epithelial lineage hierarchy remains inadequately defined. Recent lineage-tracing studies have implied the existence of prostate luminal epithelial progenitors with extensive regenerative capacity. However, this capacity has not been demonstrated in prostate stem cell activity assays, p...

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Bibliographic Details
Main Authors: Kwon, Oh-Joon, Valdez, Joseph, Zhang, Li, Zhang, Boyu, Wei, Xing, Su, Qingtai, Ittmann, Michael M, Creighton, Chad J, Xin, Li
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167399/
https://ncbi.nlm.nih.gov/pubmed/25048699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5416
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