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DNA Methylation Increases Nucleosome Compaction and Rigidity
Cytosine methylation on CpG dinucleotides is an essential epigenetic modification in eukaryotes. How DNA methylation modulates nucleosome structure and dynamics has been a long standing question. We implemented a single molecule method to monitor effects of DNA methylation on the structure and dynam...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4167393/ https://ncbi.nlm.nih.gov/pubmed/20095602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja910264z |
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