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DNA Methylation Effects on Tetra-Nucleosome Compaction and Aggregation

DNA CpG methylation has been associated with chromatin compaction and gene silencing. Whether DNA methylation directly contributes to chromatin compaction remains an open question. In this study, we used fluorescence fluctuation spectroscopy (FFS) to evaluate the compaction and aggregation of tetra-...

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Detalhes bibliográficos
Main Authors: Jimenez-Useche, Isabel, Nurse, Nathan P., Tian, Yuqing, Kansara, Bhargav S., Shim, Daphne, Yuan, Chongli
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190600/
https://ncbi.nlm.nih.gov/pubmed/25296315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.05.055
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