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Valnoctamide enhances phasic inhibition: a potential target mechanism for the treatment of benzodiazepine-refractory status epilepticus

Valnoctamide (VCD), a derivative of valproate, suppresses electrographic seizures in animal models of status epilepticus (SE), even when the seizures are resistant to benzodiazepines (BZDs). We therefore tested the effect of VCD on miniature inhibitory post-synaptic currents (mIPSCs) in CA1 pyramida...

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Detaylı Bibliyografya
Asıl Yazarlar: Spampanato, Jay, Dudek, F. Edward
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167227/
https://ncbi.nlm.nih.gov/pubmed/24995528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.12702
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